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DSIP (Delta Sleep Inducing Peptide)

Advanced Support for Sleep, Cognitive Repair, and Neuroprotection

DSIP: Restorative Sleep, Cognitive Repair, & Neuroprotection

DSIP is a neuropeptide that promotes restorative sleep, supports cognitive repair, and provides neuroprotection. It enhances deep sleep, REM sleep, reduces stress, and aids in brain recovery without causing sedation.

Benefits of DSIP

  • Improved Sleep Quality: Promotes deeper restorative sleep and REM sleep without sedation.

  • Cognitive Repair: Supports brain recovery and function, especially after traumatic brain injury.

  • Stress Reduction: Calms the brain, reduces excitatory signals, and alleviates stress and anxiety.

  • Neuroprotection: Protects neurons and regulates brain excitability, supporting long-term brain health.

  • Hormonal Support: Helps regulate luteinizing hormone (LH), indirectly supporting testosterone production in men.

Common Uses:

  • Enhances deep, restorative sleep

  • Supports REM sleep without sedation

  • Promotes cognitive and brain repair

  • Reduces stress and anxiety

  • Provides neuroprotection and supports brain recovery

Sandra Rodriguez

Lost 40 lbs in 6 months.

The Treatment Stack (3-Month Packages):

GLP-1 Weight Loss With Customized Peptide Plan — $9,000 / 6 months

Comprehensive HRT Plan — $1800 / 6 months

“Never in a million years did I think I would feel as confident and empowering as I do today, I didn’t even know it was possible to feel as amazing as I do today. I feel better at 33 years old than when I was in my 20’s.” – Sandra R., 33 yo, Texas, Private Company Executive & Mother of a toddler

Real Patient Transformations at TRTMD

Delta Sleep Inducing Peptide (DSIP) is a naturally occurring neuropeptide that plays a vital role in regulating sleep, supporting cognitive repair, and providing neuroprotection. It enhances deep sleep (delta wave activity) and REM sleep without causing sedation, allowing the body and brain to recover naturally.

DSIP also reduces stress by calming excitatory brain activity and promotes brain repair, making it valuable for individuals recovering from traumatic brain injuries, sleep disturbances, or chronic stress. At TRT MD, DSIP is used as a safe, scientifically-backed solution to improve sleep quality, support neurocognitive function, and enhance overall well-being.

Our Process

Getting Started with TRTMD Is Simple

Follow our simple three-step process to restore your energy, balance, and overall wellness.

Schedule Your Consultation

Start with a quick phone call where we happily & personally answer all your questions and arrange an in-office visit with one of our expert physicians.

Receive a Treatment Plan

After your bloodwork, meet with a physician for 60–90 minutes. They’ll review your results and create a plan so you can begin therapy the same day.

Regain Your Vitality & Drive

Most patients see results within two weeks. Our team will stay in touch with support and proactive check-ins throughout your treatment.

Why DSIP is Offered by TRT MD

TRT MD provides personalized DSIP therapy to improve sleep, brain repair, and stress management. Treatment plans are tailored for optimal dosage and effectiveness. DSIP is often combined with hormone optimization or nutritional support to create a holistic approach to sleep, cognitive health, and neuroprotection.

Improving Sleep and Reducing Stress with DSIP

DSIP promotes restorative sleep by enhancing delta and spindle wave activity and REM sleep. It also reduces stress by calming excitatory brain signals, supporting recovery from sleep disturbances, alcohol or drug withdrawal, and chronic stress.

How DSIP Works

DSIP enhances sleep by increasing delta and spindle wave activity, which are crucial for deep sleep and motor regulation. It promotes REM sleep, essential for memory consolidation. DSIP reduces excitatory brain activity, providing stress relief, neuroprotection, and cognitive recovery. It crosses the blood-brain barrier, directly influencing brain function and repair.

Who Should Use DSIP

DSIP is ideal for individuals who:

  • Struggle with insomnia or sleep disturbances

  • Are recovering from brain injuries or neurological conditions

  • Experience chronic stress, anxiety, or mood disorders

  • Seek to enhance cognitive function and neuroprotection

  • Want restorative sleep without sedation or tolerance

Success Stories

Trusted Care, Proven Patient Results

Discover how TRTMD Health Clinic helps patients restore balance, regain vitality, and build lasting confidence.

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Victoria Morales profile picture
Victoria Morales
September 23, 2025
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I love dr. Ross, and staff. They are all wonderful. I love the environment, the love care, and the health treatments I get. I feel Dr. Ross really cares and takes care of his patients with so much love and respect. Thanks Dr. Ross and everyone. Thanks Kara for your care it was wonderful.
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Jerry Stratford
September 19, 2025
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I’d like to share my experience with TRTMD! To say I am blow away by the results I have gotten in such a short period of time wouldn’t do this process justice! I’m 8 weeks into my journey with TRT and it has been life changing! I am down 55 lbs over the last 8 weeks. My T levels went from 220 to 891 and I feel phenomenal! I literally feel like a new man! The staff/team at TRTMD are absolutely amazing in these knowledge, care and support! Going in I was hesitant about the process and all of it in general. After my first appointment I was completely comfortable with everything and excited to get rolling! I couldn’t recommend this clinic or their process more! 10 of out 10. Life changing experience!
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John Jonesboro
September 10, 2025
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I've been with TRT MD since 2021. Very knowledgeable and thorough. Highly recommend.
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Michelle Reese
August 25, 2025
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Such a wonderful office with top notch staff! Highly recommend!
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Roger Black
August 25, 2025
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Very attentive and receptive of my needs!!! Highly Recommend
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Wayne Sarro
July 25, 2025
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I started my therapy regimen in 2025. Dr. VanAntwerp started me on a treatment regiment on my first visit. I am in martial arts and am thoroughly pleased with results after a month. Recovery time is faster, energy levels are up and muscle is being maintained while loosing noticeable fat in the midsection. Dr. VanAntwerp also recommended observation on other possible underlying medical conditions. The staff is extremely helpful, knowledgeable and friendly as well. It has been well worth the time and money for a thorough treatment plan. HIGHLY RECOMMENDED!!!
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Kenny Kasubinski
July 24, 2025
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Great experience. Front desk very helpful. Dr VanAntwerp is amazing
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Bear Bryant
July 9, 2025
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Dr Ross and the ladies here are amazing! Super helpful with explanations and suggestions. Very through with everything they have done. 10 out 10 I always recommend.
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Michael Fitzpatrick
June 17, 2025
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Absolutely Life-Changing Experience with TRTMD Working with TRTMD has been one of the best decisions I’ve ever made for my health and well-being. From day one, their staff provided the best customer service I’ve ever experienced. Not just in healthcare, but anywhere. They’re professional, incredibly responsive, and genuinely care about your progress. Before TRTMD, I felt like I was constantly spinning my wheels: tired, unmotivated, and not myself. Since starting treatment, the difference has been tremendous. My energy, mood, focus, and performance have all improved dramatically. I truly feel like myself again, actually, better than I’ve felt in years!! TRTMD is what modern medical care should be: personalized, attentive, and results-driven. They take the time to listen, to explain, and to optimize your treatment with real expertise. I can’t recommend them enough. If you’re considering hormone therapy or even just questioning how you feel, TRTMD is the place to go. They’ve changed my life.
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Cristian Montoya
June 6, 2025
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Great experience so far and very professional.

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