Las Vegas has more than a dozen ketamine providers — and the differences between them are not cosmetic. The clinic that runs a 30-minute infusion with minimal screening is not offering the same treatment as one where a board-certified physician assesses your full history, titrates dosing to your metabolism, and has a plan for what happens after session six.
This guide ranks the best ketamine clinics in Las Vegas for 2026, evaluated on four criteria: physician oversight, protocol depth, integration support, and pricing transparency.
It also covers what to look for when you call, what each delivery modality actually means, and what it all costs, because most clinic websites won’t tell you.
The Best Ketamine Clinics in Las Vegas
1. TRTMD Health Clinic — Best for Physician-Led, Integrated Care
Location: 1215 S. Fort Apache Rd, Suite 230, Las Vegas, NV 89117
Phone: (725) 220-3890
Modality: IV infusion
Treats: Depression, anxiety, PTSD, chronic pain
TRTMD is the only ketamine provider in Las Vegas operating inside a full physician-led hormone and wellness clinic — which matters more than it might first appear. Depression, persistent fatigue, and mood instability frequently have a hormonal or metabolic driver, and a clinic that can assess and treat those underlying factors alongside ketamine is treating the whole picture, not just the presenting symptom.
Treatment is led by Dr. Ross VanAntwerp, a board-certified internal medicine physician with more than a decade of experience in hormone and wellness medicine. TRTMD is LegitScript verified — a regulatory credibility marker that signals proper licensing, staff credentialing, and compliance standards, and one that most standalone ketamine clinics do not hold.
If you’re also dealing with low testosterone, perimenopause, or weight-related metabolic disruption that may be compounding your mental health symptoms, TRTMD is the only Las Vegas clinic where you can address all of it under one roof. Pricing is discussed at consultation — call (725) 220-3890 to speak with the clinical team.
Best for: Patients who want a board-certified physician overseeing treatment, or who are managing co-occurring hormonal or metabolic issues alongside depression, anxiety, or PTSD.
2. Klarity Clinic — Established Provider in Nevada
Location: 5145 South Durango Drive, Suite 103, Las Vegas, NV 89113
Modality: IV, IM, oral ketamine; NAD+ co-treatment available
Treats: Depression, anxiety, PTSD, addiction, chronic pain
Klarity Clinic was the first practice to bring ketamine therapy to Nevada, opening in February 2016 — well before most of the current Las Vegas market existed. That decade of clinical experience is meaningful: the protocols are refined, the edge cases have been seen, and the outcomes data is more substantial than at clinics that opened in the last two or three years.
Led by Dr. Henry Liang, DO, Klarity reports an 85% symptom improvement rate across its patient population and offers a broader range of delivery modalities than most competitors, including IV, intramuscular, and oral ketamine alongside NAD+ infusions. The clinic has since expanded into a Wellness Lodge retreat model for patients who want an immersive, multi-day treatment experience.
One honest limitation: Klarity’s Las Vegas location does not offer in-house psychotherapy integration. If you want a therapist present during or formally integrated into your sessions, you’ll need to arrange that separately or look at Calm Clinic.
Best for: Patients who want the most experienced and clinically established provider in Nevada, and who may benefit from NAD+ co-treatment or a broader modality selection.
3. Calm Clinic
Location: 4029 Dean Martin Drive, Las Vegas, NV 89103
Modality: IV infusion, sublingual lozenges
Treats: Depression, anxiety, PTSD, ADHD, bipolar disorder, addiction
Most ketamine clinics in Las Vegas administer the infusion and send you home. Calm Clinic is one of the few that treats the psychological integration work — what you do with the neuroplasticity window that ketamine opens — as equally important as the infusion itself.
Led by Dr. Sam Zand and Dr. Michael Popov, the clinical team includes psychiatrists, psychologists, and therapists offering CBT and psychodynamic therapy alongside ketamine treatment. This is the model that research increasingly supports: the infusion may create the conditions for change, but structured therapeutic work appears to extend and deepen the outcomes.
If you’ve had ketamine elsewhere and felt the effects diminish after a few weeks without knowing what to do with the experience, a KAP (Ketamine-Assisted Psychotherapy) model is worth understanding before you book again.
Best for: Patients for whom the psychological integration layer is as important as the pharmacological treatment — particularly those with trauma, complex PTSD, or a history of relapse after infusion-only protocols.
4. Desert Ketamine Clinic
Location: Henderson, NV (serving the greater Las Vegas valley)
Modality: IV infusion; Ganglion Nerve Block for PTSD
Treats: Depression, anxiety, PTSD, pain, addiction
Desert Ketamine Clinic opened in February 2016 alongside Klarity, making it one of the two original ketamine providers in the valley. What distinguishes it is the clinical background of its founder: Dr. Christian Munk is the Chair of Anesthesia at Valley Hospital, which means his understanding of ketamine as a pharmacological agent is grounded in decades of anesthetic administration at the hospital level.
The clinic also offers Ganglion Nerve Block — a sympathetic nerve block procedure used to treat PTSD — which is distinct from standard ketamine infusions and not widely available in the Las Vegas market. Reviewers consistently note competitive pricing and straightforward, professional care without the premium-tier experience markup of some competitors.
Best for: Patients who prioritise anesthesiology-level clinical oversight, or who are specifically interested in Ganglion Nerve Block for PTSD alongside or instead of standard ketamine infusions.
5. Las Vegas Ketamine
Location: 3650 N Rancho Drive, Suite 110, Las Vegas, NV 89130
Modality: IV infusion
Treats: Depression, anxiety, PTSD, OCD, chronic pain, suicidal ideation
Las Vegas Ketamine is a veteran-owned practice and the most affordable confirmed provider in the valley, with a 6-session package at $2,700 — meaningfully below the market average of $3,000–$3,600 for comparable protocols. Discounts are available for veterans, first responders, and active duty military, and the clinic is a member of the American Society of Ketamine Providers (ASKP), which sets baseline professional standards for the field.
The clinic is open seven days a week, which is uncommon in the Las Vegas market and matters practically: the standard depression protocol requires six infusions over two to three weeks, and scheduling flexibility affects whether you can actually complete the series without interruption.
Best for: Patients for whom cost is a meaningful constraint, veterans and first responders, and those who need scheduling flexibility across the week.
6. Delve Psychiatry
Location: Las Vegas, NV
Modality: IV infusion
Treats: Treatment-resistant depression, anxiety, PTSD
Delve Psychiatry runs a psychiatry-integrated model — meaning ketamine treatment is situated within, rather than separate from, ongoing psychiatric care. Dr. Reitano completed advanced training at the Ketamine Research Institute with a specialisation in ketamine infusion therapy for depression, and the practice customises dosing based on each patient’s metabolism, current medications, and psychiatric history rather than applying a standard protocol across the board.
If you’re on a complex medication regimen — particularly MAOIs, benzodiazepines, or lithium — or if previous ketamine experiences have produced inconsistent results, a psychiatry-led clinic with detailed medication management is a different level of clinical oversight than most infusion-only providers offer.
Best for: Patients with complex psychiatric histories, difficult medication interactions, or prior ketamine treatment that didn’t produce expected results.
What Separates a Good Ketamine Clinic from a Mediocre One
Las Vegas now has enough ketamine providers that the variation in quality is substantial. These are the five questions worth asking before you book — and what the answers tell you.
Who administers and monitors your infusion?
The meaningful distinction is not just physician vs. nurse — it’s whether the person overseeing your infusion is clinically equipped to respond if something goes wrong, and whether their background includes pharmacological experience with ketamine specifically.
A board-certified anesthesiologist or psychiatrist-led protocol carries different clinical accountability than an RN-monitored infusion with a physician technically available by phone.
What happens before your first session?
A clinic that conducts a thorough psychiatric assessment before treating you — not just an intake form — is doing something that directly affects whether the treatment is appropriate, what dose is right, and whether your current medications create any interactions.
Ask specifically: will I speak with a physician before my first infusion, and what does that evaluation include?
What is the integration support?
Most Las Vegas clinics administer the infusion and schedule your next appointment. The research on ketamine-assisted psychotherapy increasingly suggests that structured therapeutic work in the days following an infusion extends outcomes — because the neuroplasticity window ketamine may open is an opportunity that closes without deliberate use.
Ask whether the clinic offers integration sessions, and whether they’re included or billed separately.
What is the maintenance plan?
Ketamine’s antidepressant effects may diminish over time without booster infusions — typically every four to eight weeks for maintenance, though this varies by patient. A clinic with a clear answer to “what happens after my initial six sessions?” has thought past the sale.
A clinic that hasn’t is optimising for throughput.
Will they give you a price before you commit?
Pricing opacity is common in this category, but there’s a difference between “we customise pricing to your treatment plan” and “we won’t quote you anything until you’re in the room.”
A clinic that won’t give you a meaningful cost range in advance is making it harder for you to make an informed decision — which benefits them, not you.
IV vs Spravato vs At-Home: What Type of Treatment Are You Looking At?
If you saw an unfamiliar term in the listings above, here’s what the three main delivery modalities actually mean for your experience, your eligibility, and your cost.
IV infusion
The most widely available and most studied form of ketamine therapy.
It’s administered intravenously over 40–60 minutes in a clinical setting, requires a driver home, and delivers the highest bioavailability of any modality. Most of the Las Vegas clinics on this list use IV infusions. It is not covered by insurance for mental health conditions in most cases.
Spravato (esketamine)
The only FDA-approved ketamine-derived treatment for depression. It’s administered as a nasal spray in a REMS-certified clinical setting, requires two hours of post-dose monitoring, and — unlike IV ketamine — may be covered by major insurance when medically indicated for treatment-resistant depression.
If insurance coverage matters to you and you meet the clinical criteria for Spravato, it’s worth asking specifically whether a clinic is REMS-certified before assuming IV infusion is your only option.
At-home sublingual ketamine (delivered via telehealth)
Uses oral lozenges or tablets prescribed remotely and self-administered at home.
It’s lower cost, lower intensity, and appropriate for moderate presentations — but it’s not the right tool for severe treatment-resistant depression, complex trauma, or cases where close clinical monitoring matters.
How Much Does Ketamine Therapy Cost in Las Vegas?
IV infusions in Las Vegas typically run $400–$600 per session.
A standard 6-session protocol costs $2,700–$3,600 depending on the clinic, with Las Vegas Ketamine at the low end ($2,700 confirmed) and premium-tier or integration-inclusive providers toward the higher end. Maintenance infusions after the initial series typically run $400–$500 per session.
Spravato is covered by most major insurance plans when medically indicated for treatment-resistant depression — which can substantially change the financial picture if you qualify.
Without insurance, it runs $800–$1,200 per session including the mandatory monitoring period, making it more expensive than IV infusions out of pocket.
At-home sublingual programs through telehealth platforms typically run $99–$200 per session, with initial 4–6 session programs starting around $600. This is the lowest cost entry point, though the clinical intensity is correspondingly lower.
Insurance does not cover IV ketamine infusions for mental health conditions in the vast majority of cases. Some clinics offer third-party financing; all accept major credit cards.
If you’re a veteran, ask specifically about VA-affiliated pricing or veteran discounts before assuming the published rate applies to you.
For TRTMD’s current pricing, call (725) 220-3890 — the clinical team discusses treatment costs as part of the initial consultation.
Next Steps
Ask every clinic you’re considering: what is your protocol after the initial infusion series ends?
A well-run clinic will tell you: what your maintenance schedule will look like, what metric they use to assess whether the initial series worked, and what the plan is if it didn’t.
A clinic that doesn’t have a clear answer — or that hasn’t thought past session six — is a clinic that’s treating your booking as the endpoint rather than your outcome.
That question, more than any other on this list, separates the providers worth your time from the ones worth skipping.
Ready to Discuss Ketamine Therapy at TRTMD?
At TRTMD, ketamine therapy is physician-led, personalised to your history and presentation, and — uniquely in the Las Vegas market — situated within a clinic that can also assess and address the hormonal and metabolic factors that frequently drive the symptoms ketamine is being asked to treat.
If you want to speak with a physician about whether ketamine therapy is appropriate for you, and how it fits alongside any other treatment you’re considering, call (725) 220-3890 or book a consultation online.
